Phenotypes Associated with This Genotype

Genotype
MGI:7593761

• Allelic Composition: Socs4^m1Nch/Socs4^m1Nch
• Genetic Background: C3H/He-Socs4^m1Nch

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:241977 )

N • normal thymocyte development and composition of peripheral immune cells under steady-state conditions

increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality ( J:241977 )

• increased lung viral load, disease progression (weight loss) and mortality after intranasal (i.n.) inoculation with 10<3> pfu of influenza strain H3N2 A/Hong Kong x31 (X31)

growth/size/body

growth/size/body region phenotype ( J:241977 )

N • no obvious phenotype

embryo

embryo phenotype ( J:241977 )

N • viable

mortality/aging

increased susceptibility to Orthomyxoviridae infection induced morbidity/mortality ( J:241977 )

• increased lung viral load, disease progression (weight loss) and mortality after intranasal (i.n.) inoculation with 10<3> pfu of influenza strain H3N2 A/Hong Kong x31 (X31)

reproductive system

reproductive system phenotype ( J:241977 )

N • fertile