Phenotypes Associated with This Genotype

Genotype
MGI:7581987

• Allelic Composition: Ano9^em1Uoh/Ano9^em1.1Uoh; Tg(CMV-cre)1Cgn/0
• Genetic Background: involves: BALB/cJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

taste/olfaction

abnormal olfactory sensory neuron physiology ( J:344977 )

• freshly isolated olfactory sensory neurons elicit cAMP-evoked currents with markedly reduced amplitudes

impaired olfaction ( J:344977 )

• reduced electro-olfactogram responses to odorant containing air puffs

• olfactory bulb responses (calcium signals) are significantly reduced compared to controls

behavior/neurological

abnormal olfactory behavior ( J:344977 )

• fail to show a preference for peanut butter odor

• fail to show an aversive reaction to 2-methyl butyric acid

• following reward training, fail to show preference for the trained scent, carvone

nervous system

abnormal olfactory sensory neuron physiology ( J:344977 )

• freshly isolated olfactory sensory neurons elicit cAMP-evoked currents with markedly reduced amplitudes

respiratory system

abnormal olfactory sensory neuron physiology ( J:344977 )

• freshly isolated olfactory sensory neurons elicit cAMP-evoked currents with markedly reduced amplitudes