Phenotypes for Fignl1 Tg(Stra8-cre)1Osb MGI:7546966 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Fignl1^tm1Osb/Fignl1^tm1.1Osb Tg(Stra8-cre)1Osb/0
Genetic Background	involves: C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fignl1^tm1.1Osb mutation (0 available); any Fignl1 mutation (60 available)
Fignl1^tm1Osb mutation (0 available); any Fignl1 mutation (60 available)
Tg(Stra8-cre)1Osb mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

oligozoospermia ( J:342157 )

• 6-fold lower than in control mice with reduced numbers of late spermatocytes and spermatids

abnormal chromosomal synapsis ( J:342157 )

arrest of male meiosis ( J:342157 )

• abnormal meiotic recombination with cells fully lost before pachynema

cellular

oligozoospermia ( J:342157 )

• 6-fold lower than in control mice with reduced numbers of late spermatocytes and spermatids

abnormal chromosomal synapsis ( J:342157 )

arrest of male meiosis ( J:342157 )

• abnormal meiotic recombination with cells fully lost before pachynema

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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