Phenotypes Associated with This Genotype

Genotype
MGI:7545183

• Allelic Composition: Elac2^em1Afi/Elac2^em1Afi
• Genetic Background: C57BL/6N-Elac2^em1Afi

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal prostate gland anterior lobe morphology ( J:336403 )

• disarrayed nuclei at age 30 weeks

• branching into lumen at age 30 weeks

• grade 2 lesions at age 30 weeks

prostate gland anterior lobe hyperplasia ( J:336403 )

• at ages 10 and 30 weeks

abnormal prostate gland dorsolateral lobe morphology ( J:336403 )

• stromal thickening in dorsal lobe at age 10 weeks

• papillary structures protruding into lumen at age 30 weeks

• focal grade 2 lesions at age 30 weeks

• cell crowding at age 30 weeks

• normal lateral lobe morphology at ages 10 and 30 weeks

prostate gland dorsolateral lobe hyperplasia ( J:336403 )

• dorsal lobe at age 30 weeks

prostate gland hyperplasia ( J:336403 )

• hyperplasia of dorsal lobe at age 30 weeks and anterior lobes at ages 10 and 30 weeks

prostate gland inflammation ( J:336403 )

• at age 30 weeks

immune system

prostate gland inflammation ( J:336403 )

• at age 30 weeks

reproductive system

reproductive system phenotype ( J:336403 )

N • normal ventral and lateral lobe morphology at ages 10 and 30 weeks

abnormal prostate gland anterior lobe morphology ( J:336403 )

• disarrayed nuclei at age 30 weeks

• branching into lumen at age 30 weeks

• grade 2 lesions at age 30 weeks

prostate gland anterior lobe hyperplasia ( J:336403 )

• at ages 10 and 30 weeks

abnormal prostate gland dorsolateral lobe morphology ( J:336403 )

• stromal thickening in dorsal lobe at age 10 weeks

• papillary structures protruding into lumen at age 30 weeks

• focal grade 2 lesions at age 30 weeks

• cell crowding at age 30 weeks

• normal lateral lobe morphology at ages 10 and 30 weeks

prostate gland dorsolateral lobe hyperplasia ( J:336403 )

• dorsal lobe at age 30 weeks

prostate gland hyperplasia ( J:336403 )

• hyperplasia of dorsal lobe at age 30 weeks and anterior lobes at ages 10 and 30 weeks

prostate gland inflammation ( J:336403 )

• at age 30 weeks

mortality/aging

mortality/aging ( J:336403 )

N • normal lifespan