Phenotypes Associated with This Genotype

Genotype
MGI:7540837

• Allelic Composition: Tg(Myh6-TNNI3K)#Dmar/0; Tnni3k^B/Tnni3k^B
• Genetic Background: involves: C57BL/6J * DBA/2J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

increased response of heart to induced stress ( J:154116 )

• increased left-ventricular end diastolic diameter (LVEDD) and left-ventricular end systolic diameter (LVESD) after transverse aortic constriction (TAC)

• reduced fractional shortening at age 4 and 8 weeks after TAC

homeostasis/metabolism

increased response of heart to induced stress ( J:154116 )

• increased left-ventricular end diastolic diameter (LVEDD) and left-ventricular end systolic diameter (LVESD) after transverse aortic constriction (TAC)

• reduced fractional shortening at age 4 and 8 weeks after TAC