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Phenotypes Associated with This Genotype
Genotype
MGI:7537170
Allelic
Composition
Zswim8em2Jtm/Zswim8em2Jtm
Tg(Nkx2-5-cre)9Eno/0
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Nkx2-5-cre)9Eno mutation (0 available)
Zswim8em2Jtm mutation (1 available); any Zswim8 mutation (53 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
N
• unlike germline null mice, conditional loss in hear progenitor cells does not result i neonatal lethality

cardiovascular system
• apex is less distinct
• cardiac phenotypes are less severe than in germline null mice
• dilated ventricles


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory