About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:7526467
Allelic
Composition
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+
Polr1atm1c(EUCOMM)Hmgu/Polr1atm1c(EUCOMM)Hmgu
Tg(Sox10-cre)1Wdr/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo mutation (10 available); any Gt(ROSA)26Sor mutation (1095 available)
Polr1atm1c(EUCOMM)Hmgu mutation (0 available); any Polr1a mutation (92 available)
Tg(Sox10-cre)1Wdr mutation (2 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• normal outflow tract septation in E9.5 embryos

craniofacial
• in E16 and E17 embryos
• in E16 and E17 embryos
• mandibular cleft in E14-E17 embryos
• in E17 embryos
• in E16 and E17 embryos
• in E16 and E17 embryos
• in E16 and E17 embryos

digestive/alimentary system
• in E16 and E17 embryos

growth/size/body
• mandibular cleft in E14-E17 embryos
• in E16 and E17 embryos
• in E16 and E17 embryos
• in E16 and E17 embryos

respiratory system
• in E16 and E17 embryos

skeleton
• in E16 and E17 embryos
• in E16 and E17 embryos
• mandibular cleft in E14-E17 embryos
• in E17 embryos
• in E16 and E17 embryos


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/18/2025
MGI 6.24
The Jackson Laboratory