Phenotypes Associated with This Genotype

Genotype
MGI:7516350

• Allelic Composition: Apoe^tm1Unc/Apoe^tm1Unc; Svep1^{tm1a(EUCOMM)Hmgu}/Svep1⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

abnormal artery morphology ( J:304349 )

• reduced atherosclerotic plaque burden in whole aorta and aortic arch and root after 8 weeks of HFD feeding

• reduced macrophage invasion of aortic root neointima after 8 weeks of HFD feeding

growth/size/body

growth/size/body region phenotype ( J:304349 )

N • normal body weight after 8 weeks of HFD feeding

homeostasis/metabolism

homeostasis/metabolism phenotype ( J:304349 )

N • normal plasma total cholesterol, triglycerides and glucose levels after 8 weeks of HFD feeding