Phenotypes for Nipbl Wapl MGI:7490411 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Nipbl^{Gt(EUCE313f02)1.2Hmgu}/Nipbl⁺ Wapl^tm1.1Kpfe/Wapl^tm1.2Kpfe
Genetic Background	involves: 129 * C57BL/6J * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nipbl^{Gt(EUCE313f02)1.2Hmgu} mutation (0 available); any Nipbl mutation (124 available)
Wapl^tm1.1Kpfe mutation (1 available); any Wapl mutation (169 available)
Wapl^tm1.2Kpfe mutation (0 available); any Wapl mutation (169 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

embryo

abnormal embryo size ( J:331699 )

• embryos are significantly larger than mutant mice wild-type for Wapl

• partial rescue of about 24% of reduced embryo growth phenotype

mortality/aging

preweaning lethality, complete penetrance ( J:331699 )

• none found at weaning

growth/size/body

abnormal embryo size ( J:331699 )

• embryos are significantly larger than mutant mice wild-type for Wapl

• partial rescue of about 24% of reduced embryo growth phenotype

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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