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Phenotypes Associated with This Genotype
Genotype
MGI:7489862
Allelic
Composition		 Smc3tm1.1Toshi/Smc3+
Tg(Icam5-cre)DYyos/0
Genetic
Background		 involves: C57BL/6J * DBA/2J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Smc3tm1.1Toshi mutation (0 available); any Smc3 mutation (46 available)
Tg(Icam5-cre)DYyos mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal pyramidal neuron dendrite morphology ( J:242006 )
• at 6 weeks of age, cortical layer II/III pyramidal neurons exhibit greater dendritic arbor complexity and dendrite length than in control mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory