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Phenotypes Associated with This Genotype
Genotype
MGI:7444375
Allelic
Composition		 Rr395em1Bhao/Rr395em1Bhao
Genetic
Background		 Not Specified
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No mouse lines available in IMSR.
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♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:333961 )
N
• normal T cell receptor alpha chain V-J joining
increased thymocyte apoptosis ( J:333961 )
• decreased lifespan in vitro
decreased thymocyte number ( J:333961 )
• ~30% reduction

immune system
increased thymocyte apoptosis ( J:333961 )
• decreased lifespan in vitro
decreased thymocyte number ( J:333961 )
• ~30% reduction

endocrine/exocrine glands
increased thymocyte apoptosis ( J:333961 )
• decreased lifespan in vitro
decreased thymocyte number ( J:333961 )
• ~30% reduction

cellular
increased thymocyte apoptosis ( J:333961 )
• decreased lifespan in vitro

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory