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Phenotypes Associated with This Genotype
Genotype
MGI:7442280
Allelic
Composition		 Adgrg6em2Jlp/Adgrg6em2Jlp
Edil3Tg(Sox2-cre)1Amc/Edil3+
Gt(ROSA)26Sortm1(ADGRG6)Jlp/Gt(ROSA)26Sor+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NCrl * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adgrg6em2Jlp mutation (0 available); any Adgrg6 mutation (63 available)
Edil3Tg(Sox2-cre)1Amc mutation (5 available); any Edil3 mutation (43 available)
Gt(ROSA)26Sortm1(ADGRG6)Jlp mutation (0 available); any Gt(ROSA)26Sor mutation (1095 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
lethality throughout fetal growth and development, incomplete penetrance ( J:315981 )
• when the cre transgene is inherited maternally, embryos survive to birth, regardless of the presence of the Cre transgene
embryonic lethality during organogenesis, complete penetrance ( J:315981 )
• when the cre transgene is inherited paternally, embryos do not survive past E13.5

nervous system
nervous system phenotype ( J:315981 )
N
• when the cre transgene is inherited maternally, no PNS-related phenotypes are observed

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory