Phenotypes for H2 Rr381 MGI:7439206 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	H2^dlAb1-Ea/H2^dlAb1-Ea Rr381^em5Kap/Rr381^em5Kap
Genetic Background	involves: 129S2/SvPas * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
H2^dlAb1-Ea mutation (15 available); any H2 mutation (304 available)
Rr381^em5Kap mutation (0 available); any Rr381 mutation (0 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

hematopoietic system

absent CD8-positive, alpha-beta T cells ( J:333471 )

• almost complete redirection of MHC class I-specific T cells to CD4+ lineage

immune system

absent CD8-positive, alpha-beta T cells ( J:333471 )

• almost complete redirection of MHC class I-specific T cells to CD4+ lineage

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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