Analysis Tools
mortality/aging
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• mice exhibit a higher frequency of premature postnatal death
|
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• lower than expected number of mice at birth
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growth/size/body
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• mice are smaller at weaning age than wild-type mice or either single heterozygote
|
behavior/neurological
reproductive system
sex reversal
(
J:260599
)
|
• mice exhibit a higher frequency of male-to-female sex reversal
|
vision/eye
|
• E12.5 eyes show a wider choroidal fissure than in either single heterozygote
|
|
• coloboma is much more severe than in single heterozygotes
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