Phenotypes for Gas1 Shh MGI:7386876 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gas1^tm1Fan/Gas1^tm1Fan Shh^tm1Chg/Shh^tm1Chg
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gas1^tm1Fan mutation (0 available); any Gas1 mutation (16 available)
Shh^tm1Chg mutation (2 available); any Shh mutation (48 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality, complete penetrance ( J:122159 )

• mice only survive to around E9.5

craniofacial

abnormal craniofacial morphology ( J:122159 )

• mice exhibit severe craniofacial defects

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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