Phenotypes Associated with This Genotype

Genotype
MGI:7383045

• Allelic Composition: Tg(Myh6-GAL4)G#2Vmc/0
• Genetic Background: FVB-Tg(Myh6-GAL4)G#2Vmc

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cardiovascular system

pulmonary vascular congestion ( J:330678 )

enlarged heart ( J:330678 )

• enlarged chambers

increased heart weight ( J:330678 )

• 2x increase in heart weight to body weight ratio

growth/size/body

enlarged heart ( J:330678 )

• enlarged chambers

increased heart weight ( J:330678 )

• 2x increase in heart weight to body weight ratio

abnormal body water content ( J:330678 )

• abdominal effusion (fluid accumulation)

homeostasis/metabolism

pleural effusion ( J:330678 )

liver/biliary system

abnormal liver parenchyma morphology ( J:330678 )

• necrosis

mortality/aging

premature death ( J:330678 )

• 50% of mice die from heart failure between 3 weeks and 6 months

respiratory system

pulmonary vascular congestion ( J:330678 )

pleural effusion ( J:330678 )