Phenotypes Associated with This Genotype

Genotype
MGI:7344054

• Allelic Composition: Gt(ROSA)26Sor^{tm1(Bcor*A)Vjba}/Gt(ROSA)26Sor⁺; Tmem163^{Tg(ACTB-cre)2Mrt}/Tmem163⁺
• Genetic Background: involves: 129S1/Sv * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:296645 )

• embryos die between E10.5 and E14.5 with all dead by E14.5

craniofacial

short mandible ( J:296645 )

• short and misshapen

short snout ( J:296645 )

• short and misshapen

vision/eye

abnormal eye morphology ( J:296645 )

• misshapen by E12.5

limbs/digits/tail

abnormal forelimb morphology ( J:296645 )

• small and misshapen by E13.5

nervous system

abnormal hindbrain morphology ( J:296645 )

• appears bulbous

skeleton

short mandible ( J:296645 )

• short and misshapen

growth/size/body

short snout ( J:296645 )

• short and misshapen