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Phenotypes Associated with This Genotype
Genotype
MGI:7343919
Allelic
Composition		 Bcortm1.1Vjba/Bcor+
Isl1tm1(cre)Sev/Isl1+
Genetic
Background		 involves: 129S1/Sv
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bcortm1.1Vjba mutation (1 available); any Bcor mutation (18 available)
Isl1tm1(cre)Sev mutation (1 available); any Isl1 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
persistent truncus arteriosus ( J:296645 )
• at E13.5 in 7% of embryos

mortality/aging
preweaning lethality, incomplete penetrance ( J:296645 )
• only 44% of expected mice survive to weaning

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory