Phenotypes Associated with This Genotype

Genotype
MGI:7343894

• Allelic Composition: Bcor^tm1.1Vjba/Y; Tmem163^{Tg(ACTB-cre)2Mrt}/Tmem163⁺
• Genetic Background: involves: 129S1/Sv * C57BL/6N * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and placentation, complete penetrance ( J:296645 )

♂ • die between E7.5 and E9.5

embryo

embryonic growth retardation ( J:296645 )

♂ • about a half to full day developmental delay at E7.5-E8.5

♂ • in stage matched embryos at the 8-9 somite stage abnormalities are most obvious in the trunk and brain

♂ • in stage matched embryos at the 8-9 somite stage the trunk is shorter and cardiac tissue is not prominent

nervous system

decreased forebrain size ( J:296645 )

♂

growth/size/body

embryonic growth retardation ( J:296645 )

♂ • about a half to full day developmental delay at E7.5-E8.5

♂ • in stage matched embryos at the 8-9 somite stage abnormalities are most obvious in the trunk and brain

♂ • in stage matched embryos at the 8-9 somite stage the trunk is shorter and cardiac tissue is not prominent