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Phenotypes Associated with This Genotype
Genotype
MGI:7331503
Allelic
Composition		 Cmtm5tm1c(KOMP)Wtsi/Cmtm5tm1c(KOMP)Wtsi
Tg(Plp1-cre/ERT2)1Ueli/0
Genetic
Background		 B6.Cg-Cmtm5tm1c(KOMP)Wtsi Tg(Plp1-cre/ERT2)1Ueli
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cmtm5tm1c(KOMP)Wtsi mutation (0 available); any Cmtm5 mutation (17 available)
Tg(Plp1-cre/ERT2)1Ueli mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal axon morphology ( J:327261 )
• adults show pathological appearing axons in optic nerves (axonopathy) 4 months after tamoxifen injection

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory