Phenotypes for A930024E05Rik Satb1 Tg(Rorc-cre)1Litt MGI:7311734 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	A930024E05Rik^em2Zfa/A930024E05Rik^em2Zfa Satb1^em1Zfa/Satb1^em1Zfa Tg(Rorc-cre)1Litt/0
Genetic Background	involves: C57BL/6 * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
A930024E05Rik^em2Zfa mutation (0 available); any A930024E05Rik mutation (85 available)
Satb1^em1Zfa mutation (0 available); any Satb1 mutation (47 available)
Tg(Rorc-cre)1Litt mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

increased susceptibility to bacterial infection induced morbidity/mortality ( J:259392 )

• in C. rodentium exposed mice

immune system

increased susceptibility to bacterial infection ( J:259392 )

• in C. rodentium exposed mice

increased susceptibility to bacterial infection induced morbidity/mortality ( J:259392 )

• in C. rodentium exposed mice

hematopoietic system

decreased common lymphocyte progenitor cell number ( J:259392 )

• greatly reduced absolute numbers of ILC3 cells due to reduced proliferation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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