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Phenotypes Associated with This Genotype
Genotype
MGI:7260117
Allelic
Composition
Adamts16em2(IMPC)H/Adamts16em2(IMPC)H
Genetic
Background
C57BL/6NTac-Adamts16em2(IMPC)H
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Adamts16em2(IMPC)H mutation (1 available); any Adamts16 mutation (83 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
reproductive system
N
• unexpectedly, male mice undergo normal primary sex determination and develop testes in the fetal period; adult males have no defects in testicular descent and show normal fertility at 3 and 6 months of age
• female mice are also fertile with no apparent morphological defects in the reproductive system
• adult males show a small but significant (~10%) decrease in average testis weight relative to age-matched controls
• however, adult testicular histology is normal

endocrine/exocrine glands
• adult males show a small but significant (~10%) decrease in average testis weight relative to age-matched controls
• however, adult testicular histology is normal


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory