Phenotypes Associated with This Genotype

Genotype
MGI:7256625

• Allelic Composition: Ifnar1^tm1Agt/Ifnar1^tm1Agt; Otulin^{tm1c(EUCOMM)Hmgu}/Otulin^{tm1c(EUCOMM)Hmgu}; Tg(KRT14-cre)1Cgn/0
• Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6N * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

immune system phenotype ( J:312394 )

N • normal circulating inflammatory cytokine and chemokine levels in most mice

dermatitis ( J:312394 )

• delineated inflamed skin lesions from age 6 weeks in some mice

integument

integument phenotype ( J:312394 )

N • no skin lesions and normal epidermal thickness in most mice

dermatitis ( J:312394 )

• delineated inflamed skin lesions from age 6 weeks in some mice