About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6888148
Allelic
Composition		 Rab7btm1Ciphe/Rab7btm1Ciphe
Tg(Itgax-cre)1-1Reiz/0
Genetic
Background		 involves: C57BL/6N * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Rab7btm1Ciphe mutation (0 available); any Rab7b mutation (20 available)
Tg(Itgax-cre)1-1Reiz mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal dendritic cell migration ( J:321707 )
• decreased migration speed in LPS-exposed cells

hematopoietic system
abnormal dendritic cell migration ( J:321707 )
• decreased migration speed in LPS-exposed cells

cellular
abnormal lysosome morphology ( J:321707 )
• reduced number of small lysosomes per cell in LPS-exposed cells
abnormal dendritic cell migration ( J:321707 )
• decreased migration speed in LPS-exposed cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory