Phenotypes Associated with This Genotype

Genotype
MGI:6842325

• Allelic Composition: Tulp1^rd18/Tulp1^rd18
• Genetic Background: B6.Cg-Tulp1^rd18/BocJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal retina blood vessel morphology ( J:316780 )

• white retinal vessels by 1 month of age

increased susceptibility to age-related retinal degeneration ( J:316780 )

• at 1 month of age homozygotes have white retinal vessels and pigment patches and at 3 months of age retinal degeneration is evident by histology

retina spots ( J:316780 )

• by 1 month of age

abnormal eye electrophysiology ( J:316780 )

• no electroretinogram response by 2 months of age

absent visual evoked potential ( J:316780 )

cardiovascular system

abnormal retina blood vessel morphology ( J:316780 )

• white retinal vessels by 1 month of age