Phenotypes for Aptx Atm MGI:6836762 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Aptx^tm1Pmc/Aptx⁺ Atm^tm2.1Mfgc/Atm^tm2.1Mfgc
Genetic Background	involves: 129 * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Aptx^tm1Pmc mutation (1 available); any Aptx mutation (20 available)
Atm^tm2.1Mfgc mutation (1 available); any Atm mutation (168 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

decreased survivor rate ( J:316365 )

• mice exhibit reduced survivability with 52% of mice still alive at 400 days of age

neoplasm

increased thymoma incidence ( J:316365 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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