reproductive system
• velocity parameters including average path velocity (VAP), straight line velocity (VSL) and curvilinear velocity (VCL) are all significantly reduced, as observed in mice homozygous for the Kif9em1Osb allele
• however, the % of motile spermatozoa is comparable to than in heterozygous controls
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• sperm motility is impaired, as observed in mice homozygous for the Kif9em1Osb allele
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• when mated with wild-type females, males yield a significantly lower number of litters born per plug relative to wild-type males, as observed in mice homozygous for the Kif9em1Osb allele
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cellular
• velocity parameters including average path velocity (VAP), straight line velocity (VSL) and curvilinear velocity (VCL) are all significantly reduced, as observed in mice homozygous for the Kif9em1Osb allele
• however, the % of motile spermatozoa is comparable to than in heterozygous controls
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• sperm motility is impaired, as observed in mice homozygous for the Kif9em1Osb allele
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nervous system
N |
• mice do NOT exhibit overt hydrocephalus, consistent with mice homozygous for the Kif9em1Osb allele
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