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Phenotypes Associated with This Genotype
Genotype
MGI:6790454
Allelic
Composition		 Eif4btm1.1Smoc/Eif4b+
Tg(SFTPC-rtTA)5Jaw/0
Tg(tetO-cre)1Jaw/0
Genetic
Background		 involves: 129 * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Eif4btm1.1Smoc mutation (0 available); any Eif4b mutation (47 available)
Tg(SFTPC-rtTA)5Jaw mutation (5 available)
Tg(tetO-cre)1Jaw mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to Riboviria infection ( J:311140 )
• doxycycline-treated mice show increased susceptibility to pseudorabies virus infection, showing increased pseudorabies virus-gE in lungs and brains

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory