Phenotypes Associated with This Genotype

Genotype
MGI:6790274

• Allelic Composition: Tg(Prnp-UBQLN2)WT-lowHlp/0
• Genetic Background: involves: C57BL/6 * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:299301 )

N • normal behavior in open field, balance beam and rotarod tests

N • normal behavior in Morris water maze and fear conditioning tests

cellular

cellular phenotype ( J:299301 )

N • normal autophagy in brain

nervous system

nervous system phenotype ( J:299301 )

N • normal brain lateral ventricular volume at age 18 months

vision/eye

vision/eye phenotype ( J:299301 )

N • normal eye morphology at ages 3 and 8 weeks and 12 months