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Phenotypes Associated with This Genotype
Genotype
MGI:6766459
Allelic
Composition
Or55b10tm1Tboz/Or55b10tm1Tboz
Rr82em1Tboz/Rr82em1Tboz
Genetic
Background
involves: 129S6/SvEv * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Or55b10tm1Tboz mutation (0 available); any Or55b10 mutation (17 available)
Rr82em1Tboz mutation (0 available); any Rr82 mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
craniofacial
• in the absence of this enhancer there is reduced expression of 70 out of 131 class I olfactory receptor genes, with expression of 18 of those receptors being abolished, and the effect correlates with genomic distance with no genes outside of the class I olfactory receptor cluster being affected

taste/olfaction
• in the absence of this enhancer there is reduced expression of 70 out of 131 class I olfactory receptor genes, with expression of 18 of those receptors being abolished, and the effect correlates with genomic distance with no genes outside of the class I olfactory receptor cluster being affected
• homozygous loss of this enhancer results in a lack of aversion to carboxylic acids

nervous system
• in the absence of this enhancer there is reduced expression of 70 out of 131 class I olfactory receptor genes, with expression of 18 of those receptors being abolished, and the effect correlates with genomic distance with no genes outside of the class I olfactory receptor cluster being affected

respiratory system
• in the absence of this enhancer there is reduced expression of 70 out of 131 class I olfactory receptor genes, with expression of 18 of those receptors being abolished, and the effect correlates with genomic distance with no genes outside of the class I olfactory receptor cluster being affected

growth/size/body
• in the absence of this enhancer there is reduced expression of 70 out of 131 class I olfactory receptor genes, with expression of 18 of those receptors being abolished, and the effect correlates with genomic distance with no genes outside of the class I olfactory receptor cluster being affected


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/28/2026
MGI 6.24
The Jackson Laboratory