Phenotypes Associated with This Genotype

Genotype
MGI:6761766

• Allelic Composition: Cables2^{tm1(KOMP)Vlcg}/Cables2^{tm1(KOMP)Vlcg}
• Genetic Background: C57BL/6NTac-Cables2^{tm1(KOMP)Vlcg}
• Cell Lines: 16085A-D3

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:309963 )

• no mice are detected at or beyond E12.5

embryo

embryonic growth arrest ( J:309963 )

• growth and patterning arrest in gastrulation

embryonic growth retardation ( J:309963 )

• mice do not progress beyond early- to mid-gastrula cylindrical morphology

decreased embryo size ( J:309963 )

• at E7.5 to E9.5

growth/size/body

embryonic growth retardation ( J:309963 )

• mice do not progress beyond early- to mid-gastrula cylindrical morphology

decreased embryo size ( J:309963 )

• at E7.5 to E9.5

cellular

increased apoptosis ( J:309963 )

• at E7.5