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Phenotypes Associated with This Genotype
Genotype
MGI:6729183
Allelic
Composition		 Slxem1.1JbmuSlxl1em1.1Jbmu/Y
Genetic
Background		 involves: C57BL/6NHsd * DBA/2NHsd * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slxem1.1Jbmu mutation (0 available); any Slx mutation (5 available)
Slxl1em1.1Jbmu mutation (1 available); any Slxl1 mutation (4 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
reproductive system
abnormal spermatogenesis ( J:304511 )
• at stage 7/8 with delay in transition from round spermatids to elongated spermatids
• however, meiosis is normal as round spermatid successfully fertilize oocytes
oligozoospermia ( J:304511 )
• severe
teratozoospermia ( J:304511 )
• failure to transition from round spermatids to elongated spermatids

cellular
oligozoospermia ( J:304511 )
• severe
teratozoospermia ( J:304511 )
• failure to transition from round spermatids to elongated spermatids

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory