Analysis Tools
immune system
| N |
• mice exhibit normal dendritic cells chemotaxis toward CCL19/21 and in vivo macrophage migration into the peritoneal cavity
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• reduced migratory lymph node dendritic cells
• however, numbers are normal in the bone marrow, spleen and thymus
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• reduced antigen-specific CD8+ T cell response initiated by deficient antibody presenting cells
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• reduced in vivo migration from peripheral sites into draining lymph nodes and decreased entry into the interfollicular channels
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hematopoietic system
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• reduced migratory lymph node dendritic cells
• however, numbers are normal in the bone marrow, spleen and thymus
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• reduced antigen-specific CD8+ T cell response initiated by deficient antibody presenting cells
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