Analysis Tools
cardiovascular system
| N |
• tamoxifen-treated mice exhibit normal carotid body morphology
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• likely secondary to anemia in tamoxifen-treated
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• impaired responsiveness to hypoxia with reduced secretory rate in tamoxifen-treated mice
• lower shifted quantal charge and reduced mean charge per event in tamoxifen-treated mice exposed to mild stimuli
• reduced increase in NADH and mitochondrial function induced by hypoxia in tamoxifen-treated mice
• however, tamoxifen-treated mice exhibit normal hypercapnia and depolarization with high extracellular potassium ion, and normal secretion induced by CO2 and high potassium ion
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hematopoietic system
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• in tamoxifen-treated mice
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homeostasis/metabolism
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• decreased hypoxic ventilatory response in tamoxifen-treated mice exposed to hypoxic conditions
• however, response to hypercapnia is normal and tamoxifen-treated mice exhibit a small transient hyperventilatory response at the onset of exposure to hypoxia
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growth/size/body
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• likely secondary to anemia in tamoxifen-treated
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muscle
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• likely secondary to anemia in tamoxifen-treated
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nervous system
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• impaired responsiveness to hypoxia with reduced secretory rate in tamoxifen-treated mice
• lower shifted quantal charge and reduced mean charge per event in tamoxifen-treated mice exposed to mild stimuli
• reduced increase in NADH and mitochondrial function induced by hypoxia in tamoxifen-treated mice
• however, tamoxifen-treated mice exhibit normal hypercapnia and depolarization with high extracellular potassium ion, and normal secretion induced by CO2 and high potassium ion
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