Phenotypes Associated with This Genotype

Genotype
MGI:6717462

• Allelic Composition: Nr4a1^tm1Pcn/Nr4a1^tm1Pcn; Tg(Cr2-cre)3Cgn/0
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

increased B cell proliferation ( J:306652 )

• greater proliferation of CD45.2+ B cells when co-cultured for 72 hours with congenically marked wild-type CD45.1+ lymphocytes and anti-immunoglobulin M (anti-IgM)

hematopoietic system

increased B cell proliferation ( J:306652 )

• greater proliferation of CD45.2+ B cells when co-cultured for 72 hours with congenically marked wild-type CD45.1+ lymphocytes and anti-immunoglobulin M (anti-IgM)

immune system

increased B cell proliferation ( J:306652 )

• greater proliferation of CD45.2+ B cells when co-cultured for 72 hours with congenically marked wild-type CD45.1+ lymphocytes and anti-immunoglobulin M (anti-IgM)