Phenotypes Associated with This Genotype

Genotype
MGI:6696437

• Allelic Composition: Del(3Dcst1-Dcst2)1Nino/Del(3Dcst1-Dcst2)1Nino
• Genetic Background: involves: 129 * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

reproductive system phenotype ( J:304712 )

N • female mice exhibit normal fertility

N • sperm motility is normal

male infertility ( J:304712 )

♂

impaired fertilization ( J:304712 )

♂ • many zona-penetrated spermatozoa do not fertilize

failure of sperm-egg fusion ( J:304712 )

♂ • using mutant sperm

♂ • however, sperm are capable of recruiting the oocyte factors at the contact site