Phenotypes Associated with This Genotype

Genotype
MGI:6696403

• Allelic Composition: Mirc21^tm1.1Aven/Mirc21^tm1.1Aven; Mirc34^em1Jnch/Mirc34^em1Jnch
• Genetic Background: involves: 129S4/SvJae * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:304721 )

• lethality occurs between P21 to P28 in some mice

postnatal lethality, incomplete penetrance ( J:304721 )

• lethality occurs between P7 and P14

behavior/neurological

jumpy ( J:304721 )

• in home cages and open arena

hunched posture ( J:304721 )

abnormal locomotor coordination ( J:304721 )

• uncoordinated hind tiptoe walking

decreased locomotor activity ( J:304721 )

• slight

• however, mice exhibit normal locomotor coordination running speed, temporal composition during the step cycle, and inter-limb coordination

vision/eye

microphthalmia ( J:304721 )

blepharoptosis ( J:304721 )

growth/size/body

decreased body weight ( J:304721 )

postnatal growth retardation ( J:304721 )