Analysis Tools
reproductive system
| N |
• female mice exhibit normal fertility
• male mice exhibit normal mating behavior and reproductive tissue morphology with normal sperm counts and motility
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• severely limited sperm passage from the uterus to the oviduct due to reduced sperm to sperm adhesion
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• 4 males only produce 2 litters totaling 4 pups in 6 months
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• severely reduced with 4 males only producing 2 litters totaling 4 pups in 6 months
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• small reduction in sperm binding to cumulus-intact oocytes
• impaired binding to the zona pellucida
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cellular
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• severely limited sperm passage from the uterus to the oviduct due to reduced sperm to sperm adhesion
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