About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:6695905
Allelic
Composition		 Pde4dtm1Mct/Pde4dtm1Mct
Genetic
Background		 B6.129P2-Pde4dtm1Mct/Mmucd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pde4dtm1Mct mutation (3 available); any Pde4d mutation (184 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal behavioral response to anesthetic ( J:304450 )
• RS25344-treated mice exhibit earlier recovery than wild-type mice
• however, mice do not sleep longer than wild-type mice and normal response to treatment with roflumilast

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory