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Phenotypes Associated with This Genotype
Genotype
MGI:6514900
Allelic
Composition		 Nexntm1Chen/Nexntm1Chen
Tg(Tnnt2-cre)5Blh/0
Genetic
Background		 involves: C57BL/6 * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nexntm1Chen mutation (0 available); any Nexn mutation (28 available)
Tg(Tnnt2-cre)5Blh mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:290931 )
• all mice die before P12

cardiovascular system
dilated cardiomyopathy ( J:290931 )
• mice develop progressive dilated cardiomyopathy

muscle
dilated cardiomyopathy ( J:290931 )
• mice develop progressive dilated cardiomyopathy

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
dilated cardiomyopathy 1CC DOID:0110424 OMIM:613122
 J:290931

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory