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Phenotypes Associated with This Genotype
Genotype
MGI:6509156
Allelic
Composition		 Del(13Naip1-Naip5)1Vnce/Del(13Naip1-Naip5)1Vnce
Nlrc4em2Vnce/Nlrc4em2Vnce
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Del(13Naip1-Naip5)1Vnce mutation (2 available); any Del(13Naip1-Naip5)1Vnce mutation (1 available)
Nlrc4em2Vnce mutation (1 available); any Nlrc4 mutation (72 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
decreased lactate dehydrogenase level ( J:294930 )
• severe reduction in LDH released by bone marrow derived macrophages exposed to Salmonella Typhimurium

immune system
decreased inflammatory response ( J:294930 )
• severe reduction in inflammatory response by bone marrow derived macrophages exposed to Salmonella Typhimurium

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory