Phenotypes Associated with This Genotype

Genotype
MGI:6502658

• Allelic Composition: Map9^tm1.2Bcgen/Map9⁺
• Genetic Background: involves: 129S4/SvJaeSor * BALB/cJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal centrosome morphology ( J:299895 )

• MEFs show an increase in the percentage of cells with detached centrosomes compared with wild-type MEFs

abnormal pericentriolar material morphology ( J:299895 )

• MEFs show an increase in pericentriolar material fragmentation compared with wild-type MEFs

aneuploidy ( J:299895 )

• a large percentage of mouse embryonic fibroblasts (MEFs) are aneuploid

chromosomal instability ( J:299895 )

• MEFs show elevated rates of lagging chromosomes in anaphase indicating increased chromosomal instability