Phenotypes for Mettl3 Tg(Ddx4-cre)1Dcas MGI:6491898 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Mettl3^tm1.1Jhha/Mettl3^tm1.1Jhha Tg(Ddx4-cre)1Dcas/0
Genetic Background	involves: 129S4/SvJaeSor * BALB/c * C57BL/6 * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mettl3^tm1.1Jhha mutation (0 available); any Mettl3 mutation (45 available)
Tg(Ddx4-cre)1Dcas mutation (2 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal ovary morphology ( J:299108 )

small testis ( J:299108 )

• massive reduction in testis volume

testis degeneration ( J:299108 )

• severe degeneration

reproductive system

abnormal ovary morphology ( J:299108 )

small testis ( J:299108 )

• massive reduction in testis volume

testis degeneration ( J:299108 )

• severe degeneration

female infertility ( J:299108 )

male infertility ( J:299108 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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