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Phenotypes Associated with This Genotype
Genotype
MGI:6491477
Allelic
Composition
Mmachctm1.1(NCOM)Mfgc/Mmachctm1.1(NCOM)Mfgc
Tg(CAG-Mmachc,-GFP)1Poche/0
Genetic
Background
C57BL/6-Mmachctm1.1(NCOM)Mfgc Tg(CAG-Mmachc,-GFP)1Poche
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mmachctm1.1(NCOM)Mfgc mutation (1 available); any Mmachc mutation (32 available)
Tg(CAG-Mmachc,-GFP)1Poche mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• weanlings are on average 30% smaller than controls and remain so throughout adulthood

homeostasis/metabolism
• adults exhibit tremendously elevated levels of homocysteine in plasma
• adults exhibit tremendously elevated levels of methylmalonic acid in plasma

craniofacial
N
• mice do not exhibit any gross craniofacial abnormalities

nervous system
N
• mice do not exhibit any gross neurological abnormalities

vision/eye
N
• mice do not exhibit any gross ocular abnormalities


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory