Phenotypes Associated with This Genotype

Genotype
MGI:6491473

• Allelic Composition: Mmachc^em1.1Poche/Mmachc^em1.1Poche
• Genetic Background: involves: C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:297666 )

• Mendelian ratios of embryos are seen at E9.5 but only 3.6% at E15, indicating that mutants die between E9.5 and E15.5

growth/size/body

decreased fetal size ( J:297666 )

• E15.5 mutant is smaller

embryo

abnormal embryo turning ( J:297666 )

• E9.5 embryos have heartbeats but have yet to undergo turning

cardiovascular system

heart right ventricle hypoplasia ( J:297666 )

• E15.5 mutant shows right ventricular hypoplasia

craniofacial

abnormal craniofacial morphology ( J:297666 )

• E15.5 mutant exhibits craniofacial dysmorphia

vision/eye

anophthalmia ( J:297666 )

• E15.5 mutant is anophthalmic