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Phenotypes Associated with This Genotype
Genotype
MGI:6491437
Allelic
Composition		 N4bp1em1Vmd/N4bp1em1Vmd
Genetic
Background		 C57BL/6N-N4bp1em1Vmd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
N4bp1em1Vmd mutation (0 available); any N4bp1 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
immune system phenotype ( J:297419 )
N
• mice exhibit no substantial organ pathology or immune dysregulation
decreased interleukin-6 secretion ( J:297419 )
• in bone marrow-derived macrophages treated with poly(I:C) or LPS

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory