Phenotypes Associated with This Genotype

Genotype
MGI:6477265

• Allelic Composition: Zc4h2^em1.1Yqd/Y
• Genetic Background: involves: C57BL/6 * FVB

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:291948 )

♂ • hemizygous male pups die after birth

nervous system

abnormal spinal cord morphology ( J:291948 )

♂ • at E10.5, hemizygous male embryos show alterations in progenitor and post-mitotic neuron domains in the ventral spinal cord that are identical to those observed in homozygous female embryos

decreased motor neuron number ( J:291948 )

♂

abnormal spinal cord interneuron morphology ( J:291948 )

♂

skeleton

skeleton phenotype ( J:291948 )

♂N • limbs show normal skeleton patterning