Phenotypes Associated with This Genotype

Genotype
MGI:6467936

• Allelic Composition: Crb1^em4Jnk/Crb1^em4Jnk
• Genetic Background: involves: C57BL/6J * SJL

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

abnormal photoreceptor inner segment morphology ( J:293375 )

• within disrupted regions, photoreceptor inner segments lack electron-dense junctions due to disruption of photoreceptor-Muller contacts

retina photoreceptor degeneration ( J:293375 )

abnormal retina outer limiting membrane morphology ( J:293375 )

• mice exhibit disruptions at the outer limiting membrane; photoreceptor nuclei invade the inner segment layer, disturbing the structure of the outer retina

nervous system

abnormal photoreceptor inner segment morphology ( J:293375 )

• within disrupted regions, photoreceptor inner segments lack electron-dense junctions due to disruption of photoreceptor-Muller contacts

retina photoreceptor degeneration ( J:293375 )