Phenotypes Associated with This Genotype

Genotype
MGI:6460107

• Allelic Composition: Slc12a2^em1Dlp/Slc12a2^em1Dlp
• Genetic Background: B6.Cg-Slc12a2^em1Dlp

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:285398 )

• Background Sensitivity: mice on a congenic C57BL/6J background show decreased survival than on a mixed C57BL/6J and DBA/2J background with no mice surviving past P30

preweaning lethality, incomplete penetrance ( J:285398 )

• Background Sensitivity: mice on a congenic C57BL/6J background show decreased survival than on a mixed C57BL/6 and DBA/2 background, with mice starting to die around P15 and none surviving past P30

digestive/alimentary system

gastrointestinal hemorrhage ( J:285398 )

• blood is seen in the intestine

abnormal intestine morphology ( J:285398 )

• intestine shows tissue shrinkage

cardiovascular system

gastrointestinal hemorrhage ( J:285398 )

• blood is seen in the intestine