Phenotypes Associated with This Genotype

Genotype
MGI:6455007

• Allelic Composition: Ctrb1^em1Toth/Ctrb1^em1Toth
• Genetic Background: C57BL/6N-Ctrb1^em1Toth

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

enlarged pancreas ( J:294171 )

• in cerulein-treated mice

increased pancreas weight ( J:294171 )

• in cerulein-treated mice

abnormal pancreas physiology ( J:294035 )

• cerulein-treated mice exhibit reduced intrapancreatic chymotrypsin activation compared with control mice

increased susceptibility to induced pancreatitis ( J:294171 , J:294035 )

• mice treated with cerulein exhibit increased intrapancreatic trypsin activity, increased pancreas size and weight, edema, and more severe pancreatitis than in control mice (J:294171)

• cerulein-treated mice exhibit increased (J:294035)

homeostasis/metabolism

edema ( J:294171 )

• in cerulein-treated mice

immune system

increased susceptibility to induced pancreatitis ( J:294171 , J:294035 )

• mice treated with cerulein exhibit increased intrapancreatic trypsin activity, increased pancreas size and weight, edema, and more severe pancreatitis than in control mice (J:294171)

• cerulein-treated mice exhibit increased (J:294035)

growth/size/body

enlarged pancreas ( J:294171 )

• in cerulein-treated mice

increased pancreas weight ( J:294171 )

• in cerulein-treated mice